SQNC_PROTOCOL · NEUROGENOMIC_OS · v0.1
──Neurogenomic OS──

730K SNPs scanned·10 neurobiological systems·client-side only

SQNC maps your genetic variants to the neurobiological systems that shape your mood, focus, anxiety, and behavior — then tells you what to do about it.

Join 1 person on the waitlist.

Not sure where to start? Take the SQNC Index → Find your neurobiological archetype in 2 minutes.

DNA processed in browser — never transmitted
SQNC_CORE · MODULE_SPEC

Built different

PATHPathway-level analysis

Compound variant interactions

Most tools report one gene at a time. SQNC reads the neurobiological pathways — how your variants interact in combination, not isolation.

COMT + DAT1 + DRD2 → reward circuit profile
EVIDEvidence-based

CPIC-grounded research

Built on peer-reviewed pharmacogenomic research and CPIC clinical guidelines. Every variant mapped to published literature.

PMID references · CPIC Level A/B
PRIVPrivacy-first

Your data never leaves

Client-side processing via Web Worker. SQNC parses your raw file in the browser — nothing is uploaded to any server.

WebAssembly · No telemetry
10 MODULES · SYS_ACTIVE

10 systems, one profile

Each module maps your genetic variants to a neurobiological system.

SERSYS_ACTIVE
Serotonergic
Reuptake efficiency, synthesis rate, receptor sensitivity
SLC6A4TPH2HTR2AMAOA
5-HTTLPR s/s
rs4570625 T/T
DASYS_ACTIVE
Dopaminergic
Prefrontal clearance, reward signaling, receptor density
COMTDAT1DRD2DRD4
Val158Met Val/Val
DAT1 10R/10R
GABASYS_ACTIVE
GABAergic
Inhibitory tone, anxiety threshold, sedation response
GABRA2GAD1GABRB3
rs279858 A/A
rs769390 T/C
NESYS_ACTIVE
Noradrenergic
Alertness, stress arousal, attention regulation
NETADRA2ADBH
rs5569 G/A
rs1800544 G/G
AChSYS_ACTIVE
Cholinergic
Memory encoding, cognitive speed, neuroplasticity
ACHECHRNA7CHAT
rs17228616 A/G
rs6494223 T/C
HPASYS_ACTIVE
HPA Axis
Cortisol regulation, stress reactivity, GR sensitivity
FKBP5NR3C1CRH
rs1360780 T/T
rs41423247 C/G
METSYS_ACTIVE
Methylation
Folate cycle, homocysteine clearance, SAM/SAH ratio
MTHFRMTRRCBS
C677T A/A
A1298C A/C
CYPSYS_ACTIVE
Detoxification
Phase I/II enzyme activity, drug clearance rate
CYP2D6GSTP1NAT2
*4/*1 IM
rs1695 A/G
ECSSYS_ACTIVE
Endocannabinoid
Pain modulation, appetite, mood homeostasis
FAAHCNR1MGLL
rs324420 C/A
rs1049353 G/A
INFSYS_ACTIVE
Inflammatory
Cytokine balance, neuroinflammation, immune-brain axis
IL6TNFCRPIL1B
rs1800795 G/C
rs1800629 G/A
PIPELINE · 4 STAGES

From raw DNA to actionable insight

01INGEST

Upload your raw DNA

Export from 23andMe or AncestryDNA. SQNC parses it entirely in your browser — nothing is uploaded.

23andMe v5 · AncestryDNA · .txt .zip
02PARSE

Extract your variants

A Web Worker scans ~730K SNPs and extracts the variants relevant to each neurobiological system.

WebWorker · ~730K SNPs · rsID lookup
03ANALYZE

Pathway-level scoring

Variants are interpreted in combination — because your biology is compound, not single-gene.

Compound scoring · 10 pathway models
04PROFILE

Your neurogenomic OS

Each system gets a profile: what your variants mean, how they interact, and what you can do.

Interventions · Protocols · Risk flags
ACCESS · PRIVATE_BETA

Get early access

Join the waitlist or take the SQNC Index quiz to map your neurobiological archetype — no DNA file required.

Join 1 person on the waitlist.

Not sure where to start? Take the SQNC Index → Find your neurobiological archetype in 2 minutes.